The series "Once Upon a Time... Life" teaches about the human body and about the different systems in it with the same characters from the other "Once Upon a Time" seasons. "The good Characters" represent the body's defense mechanisms, whereas "the bad Characters" represent the viruses and bacteria that threaten to attack the human body. 
(Source: Wikipedia)

Once Upon a Time... Space differs from the rest of the Once Upon a Time titles in the sense that the series revolve on a dramatic content rather than an educational premise. The series still has a handful of educational information (such as an episode discussing the rings of Planet Saturn). 
The series succeeds Once Upon a Time... Man. It reprises almost the entire totality of the characters of the previous series and adapts them into a science-fiction context. 
The story tells about the confrontation of many big galactic powers. Among them there is the Omega Confederation, of which Earth is a member of; the military republic of Cassiop&eacute;e led by the general Le Teigneux; and a powerful supercomputer which controls an army of robots. Once Upon a Time... Space features the adventures of Pierrot (son of colonel Pierre and president Pierrette) and his friend Psi.

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