Lady Miyako was a former test subject known as "Designated #19" from the Project. She is the high priestess and leader of a temple in Neo-Tokyo and a major ally of Kaneda and Kei as the story progresses, who plays an important role in the final battle with Tetsuo Shima.

It's the year 2019, thirty-one years have passed since the start of World War III. A top-secret child with amazing powers of the mind breaks free from custody and accidentally gets a motorcycle gang involved in the project. This incident triggers psychic powers within one of the gang members, Tetsuo, and he is taken by the army to be experimented on. His mind has been altered and is now on the path of war, seeking revenge on the society that once called him weak. <br><br>
(Source: FUNimation) 

Welcome to Neo-Tokyo, built on the ashes of a Tokyo annihilated by a blast of unknown origin that triggered World War III. The lives of two streetwise teenage friends, Tetsuo and Kaneda, change forever when paranormal abilities begin to waken in Tetsuo, making him a target for a shadowy agency that will stop at nothing to prevent another catastrophe like the one that leveled Tokyo. At the core of the agency's motivation is a raw, all-consuming fear of an unthinkable, monstrous power known only as Akira.
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(Source: Kodansha USA)