Akane is Ryo&#039;s sister. They have been living together since they were little. She is very overprotective of her brother.  

Ever since their parents died a few years ago, Ryo and his sister Akane have been living alone together. Despite their difficult situation, they are still living reasonably happy and normal lives. However, everything is about to be flipped upside-down due to a secret government project. Due to increasingly low birth rates in Japan, the Japanese government is testing a program in which two young people are forced to marry. Ryo wants no part of it, but he is given little choice in the matter; his new fianc&eacute;e, Shizuka, comes to his home late one night with several dozen government issued bodyguards, who are there to ensure the success of the new couple. Unlike Ryo, Shizuka couldn&rsquo;t be more willing to go along with this new program, and eagerly goes about her wifely duties, despite his objections. With meddling friends, pushy bodyguards, and an overenthusiastic new fianc&eacute;e, Ryo&rsquo;s life has taken a turn in a direction the young man certainly didn&rsquo;t expect.
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(Source: Anime News Network)

[Blog](http://blog.excite.co.jp/matsukimiyu/)

She was a voice actress affiliated with 81 Produce. Matsuki was a graduate of Hiroshima Jogakuin Junior & Senior High School and Keio University where she majored from the Faculty of Environment and Information Studies. 

Her parents were officially against her becoming a voice actress but permitted her to move to Tokyo and visit the Keio University after she passed an entrance exam for it. After graduating from university she started pursuing her voice acting career and went at the same time to the Nichinare narration school and the Aksent voice acting school, where she later signed under after becoming professional.

She made her debut under her real name, Matsuki Mieko (松木美愛子) in 1988 on Nude Maker's PlayStation game Mikagura Shoujo Tanteidan. But changed shortly after to using a pseudonym instead as to protect her name.

In 2000 she passed an audition and became a member of newly established pop act Up Up under the Akatsuki Project label. In 2002 she got her first major role in an anime tv series, Shichinin no Nana. During the same year, in June, she quit Aksent and signed with talent agency 81 Produce. She became a regular on two radio shows, Sakurai Koubou and Cherry Bell in October 2002. The following years saw her involved with the Da Capo franchise a visual novel, adapted into an anime, where she played one of the main characters, Sagisawa Yoriko.

Matsuki had been under treatment for acute pneumonia since July 2015. She was diagnosed with a malignant lymphoma caused by the chronic active Epstein–Barr virus infection (CAEBV) and passed away on October 27th 2015. A posthumous charity event had its proceeds go to CAEBV research, which, along with the medical history of her rare case, has helped establish the disease's mechanism of infection and possible treatment.

(Source: Wikipedia)

Akane Mizuhara