Elder Misaki is a mysterious presence at the research center. He is a very powerful psychic with unspecified abilities. He erected the mystical barrier around the research center. This barrier was sensitive to individuals and kept specific people out and others inside its limits. The barrier disappeared upon his death at the beginning of the series. It is certain that Elder Misaki had the power of foresight and Mikuriya, the Kirihara brothers and Shouko hold him in high regard.   

(Source: Wikipedia) 

It is said that 70% of the human brain capacity is unused. If humans possess incredible power, it is strongly believed to be lying dormant within this region. This unused 70% brain capacity is known as "Night Head". 
The famous work 'NIGHT HEAD' is going to break the silence. They were abandoned by their parents because of the psychic power they possessed. They are the Kirihara brothers, who lived in a laboratory within a barrier-protected forest. They have escaped from the laboratory, and a new wave of 'Revolution' is about to arise. 
A new "Night Head" is about to be awakened.

The Kirihara brothers were abandoned by their parents because of their psychic powers. Since then they have lived in a laboratory within a barrier-protected forest. One day the barrier brakes and they manage to escape from the laboratory.

The world is a lonely place for Naoto and Naoya, brothers with amazing psychic powers that set them apart from humanity. Their parents cast them out–and had them imprisoned in an exploitative research center. But after they make a daring escape from the institution, Naoya has a psychic vision of an even greater threat: a deadly plague that threatens the entire world! 
(Source: Del Rey)