Professor Saikawa and Nishinosono Moe go to camp on an island where the mysterious Professor Magata Shiki has a closed laboratory. They're curious about the murder of Magata's parents, and they manage to talk their way into the lab itself. While they are inside, a dressed-up corpse is shockingly propelled out of the door of Magata's quarters! It appears she was murdered, and she won't be the last... (Source: MangaHelpers)

The story of the original Subete ga F ni Naru novel revolves around Souhei Saikawa, a member of the Saikawa Research Lab. He goes on a vacation held by the lab, and Moe Nishinosono, the daughter of his mentor, joins the group on their vacation despite not being a part of the lab. There, the two end up finding a corpse. The two work together to solve the mysteries of what becomes a serial murder case. 
 
(Source: Anime News Network)

Professor Saikawa and Nishinosono Moe go to camp on an island where the mysterious Professor Magata Shiki has a closed laboratory. They're curious about the murder of Magata's parents, and they manage to talk their way into the lab itself. While they are inside, a dressed-up corpse is shockingly propelled out of the door of Magata's quarters! It appears she was murdered, and she won't be the last...
 
(Source: MangaHelpers)

On a colleague, Professor Kita's, suggestion, Associate Professor Saikawa Souhei and his student Nishinosono Moe head to Kita's research institute, where various experiments are being conducted in a low-temperature research lab.
 
During the night a murder takes place: two graduate students are found dead in the lab.
 
How did the killer enter the locked room? How did they leave?

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