The story is set in 2020. Mamoru, an indoorsy second-year high school student, has a crush on Aya, the pretty girl who lives next door.
However, Aya is moving out due to adult reasons.
Not wanting to be separated from her, Mamoru musters up his courage and proposes a plan to run away from home.
 
(Source: Kadokawa, translated)

The mystery story and social satire begins on the day before summer vacation, when every boy in a first-year class of a downtown Tokyo middle school disappears. Was it some accident? A mass kidnapping? Actually, the boys holed themselves up in an abandoned factory on the riverbed. With support from the schoolgirls, the boys start a revolution against the adults from this "liberation zone." 

(Source: Anime News Network)

With summer vacation just beginning, all the boys in Class 2, Year 1 at a Tokyo junior high school, disappear. They barricade themselves in an abandoned factory, declare it a liberated zone, and launch a rebellion against the adults!
 
(Source: Kadokawa, translated)

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