This story is about a boy named Rokumichi Kusaba who wants to confess his feelings to Yayoi Hino, his childhood friend. Unfortunately, after choosing the place to confess, he gets crushed by a train and loses his lower half. Rokumichi then gets saved by a scientist that turns him into a monster instead of a regular human being. What is his life going to be like while being under the guise of a monster? And what will his childhood friend think?!

Note: As a part of the JUMP START initiative, the first three chapters of Ibitsu no Amalgam were published in English as Amalgam of Distortion in VIZ Media's digital Weekly Shonen Jump on the same day as the Japanese release.