Nationality: Watchers Nest
Rank: Support AndroidSize: 135 cm, 65-42-67
Special Ability: Marksmanship
Weak Point: Bug 
The Kotoko-series support android by the same name is nearly always by Lyar's side, both literally and figuratively. Appearing as a ten year old girl, she fits the role with her childlike excitement, but is nevertheless shown to be extremely capable of both flying her R.A. and handling a minigun. Her main fault is that her loyalty only extends as far as her programming, a weakness exploited by Bernard when Kotoko is reprogrammed to shoot anyone attempting to pursue him. She and Lyar seem to have a sort of older sister/younger sister relationship, and Lyar is often the one who updates Kotoko's programming when the need arises.     from wikipedia

In the 24th Century, Intergalactic Space Travel has become a reality. One of the first outposts in the far reaches of space is WATCHER'S NEST - an inflation hole drive portal - which has recently come under attack by a mysterious force known simply as GHOUL... A group of young female cadets assigned to the portal are unexpectedly thrown into a hornet's nest of trouble as they finalize their training to become an elite pilot in the Seraphim Squadron. 
(Source: DVD Collection Back Cover)

[Blog](http://blog.excite.co.jp/matsukimiyu/)

She was a voice actress affiliated with 81 Produce. Matsuki was a graduate of Hiroshima Jogakuin Junior & Senior High School and Keio University where she majored from the Faculty of Environment and Information Studies. 

Her parents were officially against her becoming a voice actress but permitted her to move to Tokyo and visit the Keio University after she passed an entrance exam for it. After graduating from university she started pursuing her voice acting career and went at the same time to the Nichinare narration school and the Aksent voice acting school, where she later signed under after becoming professional.

She made her debut under her real name, Matsuki Mieko (松木美愛子) in 1988 on Nude Maker's PlayStation game Mikagura Shoujo Tanteidan. But changed shortly after to using a pseudonym instead as to protect her name.

In 2000 she passed an audition and became a member of newly established pop act Up Up under the Akatsuki Project label. In 2002 she got her first major role in an anime tv series, Shichinin no Nana. During the same year, in June, she quit Aksent and signed with talent agency 81 Produce. She became a regular on two radio shows, Sakurai Koubou and Cherry Bell in October 2002. The following years saw her involved with the Da Capo franchise a visual novel, adapted into an anime, where she played one of the main characters, Sagisawa Yoriko.

Matsuki had been under treatment for acute pneumonia since July 2015. She was diagnosed with a malignant lymphoma caused by the chronic active Epstein–Barr virus infection (CAEBV) and passed away on October 27th 2015. A posthumous charity event had its proceeds go to CAEBV research, which, along with the medical history of her rare case, has helped establish the disease's mechanism of infection and possible treatment.

(Source: Wikipedia)

Through the long distance warp called the "Exodus Project", Worns, Ryer and the 
other crew members of "Watchers Nest" manage to escape from the Earth. Misaki, who 
was attending the final battle with "Ghoul" at that time, isn't present there and 
before her eyes, the earth changes and gets enclosed by a time barrier. 
Ryer and the others search for a way to escape from this space time maze, but the 
earth changes to various forms. Innumerable "Nows" appear due to varying time axes. 
And also Misaki, who should have disappeared because of the Exodus Project incident, 
still afortiori. Before Ryer and the others, different forms of Misaki appear. The 
Misaki from training school, the Misaki from her childhood days. 
Are these reflections caused by the conflicts that exist inside Misaki? 
She awakens a second time and when she derives the response, that history is leading 
into a completely differnet direction now. 
Will Misaki, Ryer and the others be able to find a real happy end?! 
(Source: AnimeNfo)

Kotoko-01