Yamame is a ninja and a relative of Mamoru. She remembers when Mamoru comforted her when she was little; however, she is quite disappointed after seeing the glasses-wearing person he is now. After Mamoru saves her from an animal man Chin Panji, and starts to like him, she apologizes to Mamoru. The next day, Yamame decided to enter his school.    (Taken from Wikipedia)

Kagemori Mamoru is a dowdy boy whose hair is disheveled and who wears thick glasses, but he is actually the son of a ninja family. They have protected their neighbors, the Konnyaku family, secretly for 400 years. Mamoru has personally protected their daughter, Konnyaku Yuuna, since they were in kindergarten. When Yuuna is in trouble, Mamoru puts on ninja suit and turns into a competent ninja to help her.

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Ai Shimizu is a Japanese voice actress and professional wrestler. She has a career as a singer, signed to Lantis. She has released 14 singles (including joint and character singles) and four albums. She covered Yumi Matsutoya's "Toki o Kakeru Shōjo" as the B-side of her first single "Angel Fish" in 2003. She is known to have a close relationship with Mai Nakahara, having collaborated in eight anime where most of the characters they voiced in together had close connections: DearS, Kage Kara Mamoru!, My-HiME, My-Otome, My-Otome Zwei, Please Twins!, Sola, Strawberry Panic! and the Lucky Star drama CD. Shimizu has worked sporadic professional wrestling matches since December 2013

Mamoru Kagemori is a dull high school student who's neither handsome, athletic, nor intelligent. But things aren't always as they appear. He's actually the eldest son of a 400-year-old ninja clan that specializes in protecting their neighbors, the Konnyakus. And the object of Mamoru's protection is none other than their only daughter, Yuna Konnyaku, a natural-born troublemaker!
 (Source: DrMaster)

Mamoru Kagemori is a high school student who is neither good-looking, studious nor athletic. However, he is actually a skilled ninja who secretly protects his neighbour, Yuuna Konnyaku.
 
Mamoru and Yuuna are now third year students, but their peaceful times are suddenly interrupted on the day of the opening ceremony when Marimo, a girl who claims to be Mamoru's younger sister, transfers to his school. Marimo immediately issues a challenge to Mamoru, intending to take his duty of protecting Yuuna away from him!
 
A new chapter of the popular ninja romantic comedy has started! 
(Source: Kadokawa, translated)

Yamame Hatori