Her kind plays many roles in the body, from nursery school teachers to professional killers. Therefore, she bears many faces and personalities depending on which role she is playing. By default, Macrophage is a humble, easygoing cell manifesting as a mother figure who speaks in a polite manner. However, she can brutally kill intruders without showing empathy or mercy.

(Source: cellsatwork.fandom.com)

The average human body contains about 60 trillion cells, and each of them has work to do! But when you get injured, viruses or bacteria invade, or when an allergic reaction flares up, everyone from the silent but deadly white blood cells to the brainy neurons has to work together to get through the crisis! 
 
(Source: Kodansha Comics USA)

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Mother of voice actress [Honoka Inoue](https://anilist.co/staff/129363/Honoka-Inoue). She has held a long-running gag of being 'eternally 17 years old'.

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The second season of Hataraku Saibou. 
 
Cells at Work!! continues the tale of…well…you! Set inside the human body, Cells at Work!! chronicles the life and times of everything from the oxygen-carrying Red Blood Cells to the bacteria-fighting White Blood Cells. And, of course, the dangerous viruses and villains lurking beneath the skin! 
 
(Source: Funimation) 
 
Notes: 
- The episodes were streamed two days ahead of the Japanese broadcast on Funimation beginning on Jan 8, 2021 at 2:00 JST. The regular TV broadcast started on Jan 9, 2021 at 23:30 JST. 
- The pre-screened movie "Hataraku Saibou!!" Saikyou no Teki, Futatabi. Karada no Naka wa "Chou" Oosawagi! is included as episodes 4-8 split into the broadcast.

From Akane Shimizu, winner of Shounen Sirius' Rookie Award, comes an informative tale about anthropomorthized cells!
 
Strep throat! Hay fever! Influenza! The world is a dangerous place for a red blood cell just trying to get her deliveries finished. Fortunately, she’s not alone … She’s got a whole human body’s worth of cells ready to help out! The mysterious white blood cell, the buff and brash killer T cell, the nerdy neuron, even the cute little platelets—everyone’s got to come together if they want to keep you healthy!
 
(Source: Kodansha Comics & MangaUpdates)
 
Note: Contains the spin-off one-shot "Hataraku Saibou: Kansen-hen".

A mysterious cell wearing a stylish hat appears before the regular cells, who are bored with just the same (cell division) work over and over again, every day. This mysterious cell lures the regular cells into a mischievous scheme against White Blood Cell and Killer T Cell. The regular cells enjoy working out their everyday, pent-up frustration. But, just who exactly is this cell wearing a stylish hat?
 
(Source: Anime News Network)

BD/DVD specials of Hataraku Saibou included in disc volumes 3-7.