She is a friend of Noboru Takagami (they go to the same high school but are in different class; she belongs in Class 4).  She is also in badminton club with Noboru.  Misaki has a wildly imaginative mind when it comes to Noboru, whom she has a crush on.    First appears in episode 3.

The Mizuchi bloodline has long been hunted by Yokai, or monsters. Toru and Noboru Takagami are descendents of this bloodline, and under their grandmother's discretion, are given a secret weapon to combat these monsters. It is Tenko Kugen, a fox deity who can take the shape of a man or woman at will. The mischievous deity is accompanied by a shrine maiden, Ko, who will both live with the Takagami brothers at their house. Life just got complicated. 
(Source: NIS America)

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Two brothers, Noboru and Toru grew away from the fact that their family could use the Water ki to keep demons away. However, in order to keep Toru safe after a demon goes after his life, they will need to awake the fox diety Kuugen. 
(Source: Operation Boredom)

Short comedy sketches involving Tenko &amp; Kou.

T&#333;ru and Noburo are brothers of the Takagami Family. Toru has Yin in his blood and is constantly targeted by the y&#333;kai and other creatures lurking in Japan. When T&#333;ru is targeted by one, his brother Noburo releases the fox deity K&#363;gen Tenko who protects T&#333;ru from the monster. K&#363;gen now acts as the protector of T&#333;ru and Noburo to keep them safe from any threats to them, while at the same time trying to adapt to the modern world. 

(Source: Wikipedia)

Misaki Sakura