Joe Gibson is the star major league player from the US. He continued pitching after the age of 40, and earning over 300 wins.

~!The incident with Goro's father, Honda Shigeharu, remained a heavy cross weighed upon him, driving him to remain one of the top pitchers in the MLB, so that Honda, by comparison, would be an even greater player.!~ 

~!For the Baseball World Cup, he was Team USA's ace pitcher, although at that time he was diagnosed with angina pectoris, and the doctor warned he might die if he continue pitching. However, Gibson may feel that dying on the mound pitching his best would be the only way to truly make up to Goro, Momoko, and even Honda.!~

Honda Shigeharu is a Major League batter on the rise. His son Goro is a Little League pitcher who one day hopes to follow in his father's footsteps. Hoshino Momoko is Goro's schoolteacher, and the first woman Shigeharu has been interested in since the death of Goro's mother. The destines of these three individuals will become intertwined as father and son experience both heartbreak and triumph on the baseball diamond. But when an unspeakable tragedy visits the family, it will take everything they have to pick up the pieces and reclaim their dreams.
 
(Source: Anime News Network)

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After the baseball season was over, Goro returned to Japan. There he learned from Toshi that there is going to be a Baseball World Cup the following year hosted in America. 
(Source: AniDB)

The sixth season begins after the "Baseball World Cup" has ended. Goro regained his passion for baseball in Japan thanks to his friends, and left to join the Hornets baseball team in preperation to the new season. When he arrives in America he starts to celebrate his role as a Major League pitcher at last! Goro's family and friends gathers in groups in Japan to watch Goro's debut in the Major League. However, Goro's debut is the beginning of a line of surprising happenings, that has an outcome no one expected... 

After leaving Kaido in a promise to meet them at the Koshien tournament, Goro comes back to his home town once again in an attempt to join up with his old friends. Only this time, things aren't as easy to get back in the groove of.

Next season of Major. 
After the final game of his Seishuu team against the goal he set himself, Kaidou - the team he left to play against, Gorou has no feelings of remorse anymore. Again he decides to take a step forward and challenge himself. 
Saying one more time good bye to Shimizu and his friends, he leaves for the USA, where he plans on competing in the Minor League. 
This is where Season 4 starts, in a country that`s foreign to him, a baseball style that`s unknown to him and new friends and strong rivals who share the same love to the game as him. Accompany Gorou in his neverending quest for new challenges. 
(Source: AniDB)

The story of Major follows the life of Goro Honda, from kindergarten to being a professional baseball player, seeking and overcoming tremendous challenges.

According to Weekly Shonen Sunday, a new OVA of manga "Major" was announced to be released in December. The World Series chapter, which was skipped in the TV series, will be animated. This OVA will be the final anime of Major. 
(Source: Scan of WSS)