Yu-yu is a boy living in Kanazawa, Kaga Province. He is 15 years old and in his third year of junior high school. He has the ability to sense the feeling of others, but he is troubled by the fact that he cannot say no when asked. One day, Yu-yu could no longer stand going along with his sister's hobby, so he ran away from home. The one who saves him is Megumi Okura. Megumi invites Yu-yu to a nighttime amusement park called "Wonder Hill" where her friends hang out. 
At the amusement park, Yu-yu meets Megumi, Zakusa Ishikame, and Tomari Seto, members of "Team Blackout," a group that meets to play Vanguard every night.
 
Tonight, a serious fight for the team's flag will take place. Blackout's leader, Danji Momoyama, and the mysterious and powerful fighter, Tohya Ebata. As Yu-yu stares at them, the card fight is soon eroded into a world of images. This is how Yu-yu encounters Vanguard, a world he has never seen before, and is drawn by its powerful allure - making new friends along the way. (Source: Bushiroad) 
Note: The first episode was pre-screened on March 24, 2021 on the official japanese Cardfight Vanguard youtube channel.

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One day, six cards known as the "Six Desires" were born with the power to change fate. 
Six fighters were chosen, and would come to possess those six cards. What awaited them was the “Fated Clash“, where they would fight each other until the end, and the last one standing would have any wish granted. A youth named Akina Myodo, who wants to help his frail sister, participates in the Fated Clash to have his wish granted.
 
And thus, he throws himself into battles with powerful fighters. 
(Source: Crunchyroll)

The second season of Cardfight!! Vanguard: overDress. 

After the sudden departure of a valuable friend, the future of Team Blackout is now uncertain. Yu-yu Kondou and Megumi Ookura feel frustrated for failing to prevent the inevitable, while the heavily involved Touya Ebata is trying his best to atone for past mistakes that led to this misfortune. But whatever they decide to do next, the members of Team Blackout know that they will always find their way back together through their precious card game, Cardfight Vanguard. 

(Source: MAL Rewrite)

The second season of Cardfight!! Vanguard: will+Dress. 

Yuuyu, Raika, and Touya were invited to America after their win in the "Deluxe" tournament in Japan.
They went on a tour of exhibition matches.
Danji, who had arrived earlier in America to look into the background of the Deluxe tournament at Michiru's behest, suspects a connection with the case of the missing fighters.

The third season of Cardfight!! Vanguard: will+Dress. Vanguard becomes dominated by the Uniformers. A world where everyone can become the strongest... Is the world envisioned by AI GUI ideal? Yu-yu and his friends fight for the sake of enjoyable cardfights with individuality!

Mukae Jinki have gathered 15 Fighters, and One who have chosen from winning all the Shop Tournaments. These 16 fighters will fight for the throne to be the strongest, as the Curtain for the Second Deluxe Opens!! Who will be the one to Control the fight, who will be the one to win!?

Shinobu Kajita