Sayoko is Goro's wife ~!who died with the same condition as Rika.!~

Although Goro's first impression of her was a lonely and serious girl, she is shown to have a bright personality and enjoys teasing him on many opportunities. According to Goro, she's quickly able to read through him, ~!and it's heavily implied she knew about Goro's infidelity after the desperation of learning about her condition.!~

Sayoko has a fondness for cats and holds a self-proclaimed "cat power" that allows her to get close even to easily frightened strays. She also has an interest in pottery and literature.

~!Sayoko stayed in the same hospital as Rika when she was alive and met each other for a short while; she was the only one who knew how to calm Rika down. Sayoko was the one who asked Rika to always listen to Goro.!~

After contracting hepatitis A, Ezaki Yuuichi has been confined to a hospital away from his friends and family, much to his displeasure. To relieve his boredom, he has taken to sneaking out of the hospital, usually putting himself on the receiving end of a beating from his nurse. Upon meeting a girl his age also staying in the hospital, he is immediately captivated by her beauty. Akiba Rika's personality is not quite as captivating as her beauty however. In fact, she is rather selfish, moody, and bossy. But as the two spend more time with each other, they become closer, sharing the ordinary joys and trials of a budding teenage romance, even when darkened with impending tragedy - for Rika's condition does not leave her much longer to live.<br><br>
[Written by MAL Rewrite]

[Blog](http://blog.excite.co.jp/matsukimiyu/)

She was a voice actress affiliated with 81 Produce. Matsuki was a graduate of Hiroshima Jogakuin Junior & Senior High School and Keio University where she majored from the Faculty of Environment and Information Studies. 

Her parents were officially against her becoming a voice actress but permitted her to move to Tokyo and visit the Keio University after she passed an entrance exam for it. After graduating from university she started pursuing her voice acting career and went at the same time to the Nichinare narration school and the Aksent voice acting school, where she later signed under after becoming professional.

She made her debut under her real name, Matsuki Mieko (松木美愛子) in 1988 on Nude Maker's PlayStation game Mikagura Shoujo Tanteidan. But changed shortly after to using a pseudonym instead as to protect her name.

In 2000 she passed an audition and became a member of newly established pop act Up Up under the Akatsuki Project label. In 2002 she got her first major role in an anime tv series, Shichinin no Nana. During the same year, in June, she quit Aksent and signed with talent agency 81 Produce. She became a regular on two radio shows, Sakurai Koubou and Cherry Bell in October 2002. The following years saw her involved with the Da Capo franchise a visual novel, adapted into an anime, where she played one of the main characters, Sagisawa Yoriko.

Matsuki had been under treatment for acute pneumonia since July 2015. She was diagnosed with a malignant lymphoma caused by the chronic active Epstein–Barr virus infection (CAEBV) and passed away on October 27th 2015. A posthumous charity event had its proceeds go to CAEBV research, which, along with the medical history of her rare case, has helped establish the disease's mechanism of infection and possible treatment.

(Source: Wikipedia)

The story of Hantsuki focuses on the budding relationship between the seventeen years old Y&#363;ichi Ezaki and Rika Akiba. Both are hospitalized in Y&#363;ichi's home town for their respective conditions. Y&#363;ichi has hepatitis A, while Rika has problems with a weak heart valve. These teens would then fall in love while they spend time with one another. The story is based in Ise, Mie prefecture as implied by the "Welcome to Ise" sign shown after the opening sequence in the first episode of the anime series.

Sayoko Natsume