Born into wealth, coupled with her father's prominence, Louis Fort Drake has been handed a life of Luxury. Fresh out of prep school, and not to mention graduating top of her class, Louis has just turned 18. And where else would she be off to? Louis has gone against the grain, disobeying her father's wishes and has enlisted into the SDF Academy. As a recent graduate, Louis ranked first in her unit has been assigned to Sirius Platoon, along with Manabu Yuuki.

The story begins on planet Destiny, which claimed to be where the center of the Universe is, where all the terminals of "The Galaxy Railways" are gathered. The main character, Yuuki Manabu (20 years old), carrying on his dead Father and Brother`s will, joined SDF (Space Defense Force) to protect the safety of the Galaxy Railways. SDF, in order to uphold the reputation of maintaining the best transportation schedules within the Universe, deals with accidents, natural disasters, rescue operations, space pirates along all lines of the railway. Layla Destiny Shura is a mysterious beauty unifying SDF and all lines on The Galaxy Railways. 
She possesses the ability to see the destiny of planets, human beings and living things. Even though possessing such powers, she, being a "Guardian of Destiny", is unable to tell passengers leaving this station what difficulties lies ahead of them. However, appearances of those who uses evil powers to change the destinies of these travelers triggers another of her hidden ability. "Destiny is changed by the individual`s oneself. Tomorrow`s happiness is grabbed by the individual`s own hands." In what manner will Yuuki`s destiny be seen by Layla? And, how will Yuuki deal with his destiny amidst the greatest crisis approaching The Galaxy Railways? 
(Source: AniDB)

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OVA for The Galaxy Railways.
 
In the distant future, the planets are now connected with a massive galactic railway system. The Galaxy Express 999 has crash landed on a mysterious planet. On board are The Conductor, Killian, Maetel, and Tetsuro, a ten year-old street urchin with a heart of gold. Now it’s up to the SDF Sirius Platoon to rescue them before the Herise Time Mystery—a rift in the deep axis of time and space—repeats. 
(Source: Crunchyroll)