Yoshino, the other protagonist, is a tall, masculine child who at the beginning of Wandering Son is a fifth grader in Shuichi's class. Otherwise known as Takatsuki-kun by their classmates, with an honorific used mainly with boys, Yoshino wishes to be a boy. Yoshino usually refrains from dressing in traditionally feminine clothes, such as skirts or dresses. Despite this, Yoshino's mother insists on buying such clothes for them. Shortly after becoming friends with Shuichi, Yoshino gets a boyish haircut, taking on the appearance of a boy their age, especially when Yoshino is dressed in a male school uniform. Like Shuichi, Yoshino becomes increasingly concerned and resentful about undergoing puberty, such as at the beginning of menstruation or the growth of breasts. Yoshino goes to buy a chest-flattening garment to escape the necessity of wearing a bra. Like Shuichi, Yoshino shows signs indicating gender dysphoria, though later stops thinking that way due to personal exposure to modelling.

Yoshino prefers to dress and act like a boy, but usually abstains from anything which would draw attention, such as going to school in a male uniform after entering junior high. However, Yoshino does on occasion dress in a male school uniform and go to neighboring cities while dressed as a boy; during one such time, Yoshino enjoys being hit on by an older woman. Yoshino wants to look "cool" and wears clothes which are not girlish. When teased by others, Yoshino is prone to getting emotional and is known to get violent on occasion. Yoshino takes up an interest in basketball after entering junior high school and joins the female basketball team with Chizuru Sarashina. In junior high, Yoshino decides not to get a haircut after a comment by Saori, but later cuts it back to a short, boyish style. Yoshino's family consists of a father, mother, older brother, and older sister.

Fifth grader Shuuichi Nitori is considered by most to be one of the prettiest girls in school, but much to her dismay, she is actually biologically male. Fortunately, Shuuichi has a childhood friend who shares similar feelings of gender dysphoria: the lanky tomboy Yoshino Takatsuki, who, though biologically female, does not identify as a girl. These two friends share a similar secret and find solace in one another; however, their lives become even more complicated when they must tread the unfamiliar waters of a new school, attempt to make new friends, and struggle to maintain old ones. Faced with nearly insurmountable odds, they must learn to deal with the harsh realities of growing up, gender identity, relationships, and acceptance. 
 
Lauded as a decidedly serious take on gender identity and LGBT struggles, Takako Shimura's Hourou Musuko is about Shuuichi and Yoshino's journey to discover their true selves as they enter puberty, make friends, fall in love, and face real and difficult choices. 
 
Note: The full version of Hourou Musuko was originally intended to be 12 episodes, but the programming block it aired on only had space for 11 episodes. Therefore, episodes 10 and 11 were edited together and aired on TV as episode 10. Episode 12 was aired on TV as episode 11. The full versions of episodes 10 and 11 were included on the BD & DVD releases and are included in the Hourou Musuko Specials entry.

__Height:__ 167 cm

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A Japanese voice actress. Her debut role was Yoshino Takatsuki in Hourou Musuko. She likes to draw, and she became addicted to karuta while dubbing Chihayafuru.

__Non-Anime Roles:__ ~!
Aika Tenkūbashi in "Ore ga Ojō-sama Gakkō ni "Shomin Sample" Toshite Rachirareta Ken" (dramaCD)
Andromeda in "Starly Girls -Episode Starsia-" (VG)
Ayaka Kagari in "Lord of Vermilion IV" (VG)
Ayame Itō in "Corpse Party 2 ~ DEAD PATIENT" (dramaCD)
Baizhi in "Wuthering Waves" (VG) (Japanase)
Beruno Souda in "Racing Musume" (VG)
Carmen Sandiego in "Carmen Sandiego" (cartoon)
Clarke Griffin (voiceover for Eliza Taylor) in "The 100" (Live-action TV)
Contender in Girls' Frontline (Mobile Videogame)
Diana Celestine May in "Implosion: Never Lose Hope" (VG)
Eri Kumagai in "Music Girls (Ongaku Shōjo) projects" (songCD and dramaCD)
Hannah (voiceover for Odeya Rush) in "Goosebumps" (live-action movie)
Isabella in "Gargantia on the Verdurous Planet ONLINE FLEET" (VG)
Jessica in "Granblue Fantasy" (VG)
Kana in "Tales of Link" (Mobile VG)
Kujou Sara in "Genshin Impact" (VG)
Lili in "Street Fighter X Tekken" (VG)
Linde in "Fire Emblem Heroes" (VG)
Linde in "Genei Ibunroku ♯FE" (VG)
Little Alice in "Wonderland Wars" (VG)
Mai Sakurajima in "Seishun Buta Yarō Series" (Niconico Drama)
Meria Shiranami in "Maid ga Oshieru Maou-gaku!" (Drama CD)
Nagisa in "Monster Hunter Mezeporuta Kaitakuki" (VG)
Princess Stella in "Grand Sphere" (VG) (Japanese)
Shiranui Nanami in "NORN9 Act Tune" (otome VG)
Shiranui Nanami in "NORN9 Last Era" (otome VG)
Shiranui Nanami in "NORN9 Var Commons" (otome VG)
Shiranui Nanami in "NORN9" (otome VG)
Sofia Tenma in "Racing Musume" (VG)
Sonia Blanche in "BLADE ARCUS from Shining EX" (VG)
Sonia Blanche in "Shining Resonance" (VG)
Surge in "E.X. Troopers" (VG)
Tiki is My Wife P in "Genei Ibunroku ♯FE" (VG)
Tsukuyomi in "UNDER NIGHT IN-BIRTH Exe:Late" (VG)
Urara Taguchi in "Girl Friends" (drama CD)
Wilbell Vollerslied in "Atelier Ayesha ~Tasogare no Daichi no Renkinjutsushi~" (VG)
Wilbell Vollerslied in "Atelier Escha & Logy ~Tasogare no Sora no Renkinjutsuhi" (VG)
Wilbell Vollerslied in "Atelier Shallie ~Tasogare no Umi no Renkinjutsuhi" (VG)
Kasane Randall in "SCARLET NEXUS" (VG)
Reina in "Tekken 8" (VG)!~

Fifth grade friends Shuichi Nitori and Yoshino Takatsuki have happy homes, loving families, and are well-liked by their classmates. But they share a secret that further complicates a time of life that is awkward for anyone: Shuichi is a transgender girl, and Yoshino is transgender boy. 
 
(Source: Fantagraphics)

The full versions of episodes 10 and 11 that were previously edited together into episode 10 of the TV series.